Omus,Pulse, and a new hero called The Forcemaker as well as Rampart “the living wall” of The Vigilants arrive at the scene of a disturbance in front of a bar. Suddenly a police car is thrown and it is clear that super-strength is involved. The heroes move to take the offensive and yet it is clear that the perpetrator, a blonde man in a leather jacket, is unresponsive to their presence and attempts to talk him down as he appears to be in a frenzy. Suddenly in mid-battle the man coughs up a load of black mucus and collapses. The heroes were puzzled. After Rampart healed the heroes and police he agreed to accompany The Vanguard as they sought out the bottom of this mystery. The heroes remembered talk of a strange new sickness that was sweeping across the city. The heroes brought the blonde man to a clinic at the Eagle City Center for Disease Research to learn more. There they met a man named Dr. Lague (pronounced la-goo) who said he was intent on studying the new disease. When he examined the blonde man he noted that the man was exhibiting severe symptoms of the disease including a high fever, explaining his bewildered state, large amounts of thick black mucus forming and super-strength as a result of the disease putting the body into a sort of “overclocked” state. The Doctor theorized that the combination of the fever, the frenzy and the overclocking was for victims to seek out new people to infect and to have the fever and increased exertion burn out the host’s body, killing them in about a month as symptoms increased in severity. He was to keep the man at the clinic for study but under sedation to reduce the threat he posed should he wake. Dr. Lague has the heroes fetch other subjects with outstanding symptoms so that he may fashion a vaccine for the new disease. He says he needs a woman, a child, and a metahuman that are infected and fit the bill. The Doctor has reports of three people that fit the bill, a housewife, a child of a wealthy family, and lastly, the hero Atlas. The team splits up to retrieve the housewife and child. Rampart and Forcemaker go to The Norris family mansion in order to bring Billy Norris, the young boy, to the clinic. When they arrive they are shocked to find that Billy has been recently kidnapped. Luckily a location was already decided for the exchange. Forcemaker and Rampart attacked the kidnappers in a shabby apartment building where the meeting was to take place. They informed the criminals that their mark was carrying a disease. Billy began waking up from the drugs the kidnappers had given and using his new strength began to slowly rip apart the piping that he was tied to. Rampart subdued the kidnappers while Forcemaker knocked Billy out, averting an unwanted battle with the boy. Meanwhile Omus and Pulse were on their way to the Walmuth residence (home of the housewife) when suddenly they saw a woman bounding above rooftops a few streets away shouting profanity. When they investigated they saw she was chasing a sports car with a distressed man driving. Based on the shouting they were able to determine that Mrs. Walmuth was chasing her husband who, in her frenzied state believed to be unfaithful. Omus timed attacks with her landing in order to draw attention away from Mr.Walmuth’s car. It worked. Omus grabbed her and made her a sitting duck to Pulse’s powerful (but unfortunately unpredictable) light attacks. She was defeated. The husband turned his car around,thanked the heroes, and asserted that he did not cheat on his wife. The honesty of the last statement was clearly dubious at best. Both teams returned their subjects to the clinic, regrouped and set out to bring Atlas in. The heroes immediately went to The Pad to track down Atlas. Instead they found only Lightning Lass and Elasto. They said they last saw him heading out to scout the new base of the villain Heat Spike, who had set up shop in a local Junkyard. Upon reaching the Junkyard the heroes saw the fence had a large hole that appeared to be torn open. Upon approaching the small tin-roofed shack in the yard the heroes saw Heatspike’s body suddenly punch a hole in the shack roof as he was sent flying. Atlas then leaped from the shack (punching another hole in the roof) and began beating Heatspike mercilessly, clearly payback for what happened a few weeks ago at the Bank *. ( * In Issue #0. But you fan-guards already knew that. ) The heroes were able to goad Atlas off of Heatspike and had a tough fight slugging it out with him. Courtesy of the disease Atlas had new and improved strength and invulnerability, traits that he “the extra-durable man” was already well known for. A severely battered Heatspike attempted to limp away, but the heroes caught up with him easily. Heatspike truthfully lamented that Atlas had “come out of nowhere.” and that he himself “hadn’t done anything yet.”. Begrudgingly, the heroes let him go. As they left for the clinic with Atlas, they saw Heatspike’s minions emerge from the shack. They were in even worse shape then their leader. Bruised,battered,blackeye’d, and bleeding, they limped out with severe injuries and missing teeth caused by the powerful punches of Atlas. The heroes returned to the clinic. Dr. Lague wheeled Atlas out of the room on a gurney, returned thanked the heroes for their help. As he turned to leave he failed to notice something fall out of the pocket of his lab coat. It was a tape recorder. When played the heroes heard Lague’s voice in an audio diary. The diary detailed Dr. Preston Lague suddenly becoming very sick and then finding he could control bacteria and viruses as well as communicate with them directly. The diary went further as it detailed Lague’s deliberate engineering of the plague that was sweeping the city “Lague’s disease” in order to reap profit and fame after not only discovering but curing such a deadly disease. It described his deliberate infection of the subjects weeks before the heroes brought them in. It was revealed that blonde man whom Lague referred to as Patient Zero had been infected for over a month. Lague voiced concerns over his continued life whether it was the fault of a shoddy plague, dumb luck, or Lague feared, a reaction similar to his own before gaining his powers. After having listened to the entire diary they flipped the recorder over to show a piece of masking tape where it was written to whom the tape recorder belonged. It was abbreviated to Dr.P.Lague. The heroes pocketed the recorder and headed into the other room to confront their new foe, Dr.Plague. In the next room they saw Lague had set up cells where he kept the infected subjects The Vanguard had brought. There the mad doctor stood, realizing his plan had been discovered he began to cough up black mucus and the heroes could see his muscles clearly ripple with new strength. Lague began to enter numbers into a nearby keypad, releasing the infected, and then used his strength to smash the keypad. He then proceeded in attempting to infect the heroes with all sorts of horrible, debilitating, diseases that with his powers infected the heroes almost instantly. The subjects attacked the heroes with mad fury, all except the blonde man who instead attacked Dr.Plague. After a tough fight in which Pulse nearly went toe to toe with Atlas. The subjects (apart from the blonde man)were knocked unconscious. Desperate, Doctor Plague produced a vial from his coat. In it, a luminescent fluid bubbled. Plague claimed it was the cure for his engineered plague. He threatened to smash the vial if the heroes came any closer. Omus stepped forward and as Lague lifted his arm to throw down and smash the vial, Rampart quickly used his powers to strengthen the glass, causing it to instead bounce off the ground intact toward the heroes. After knocking out the winded Lague, the heroes approached the blonde man who had fought alongside them against the doctor. The man said he had been sick for over a month which to him was odd for he could not remember ever being sick in the past few years. He surmised that his immune system had managed to beat back the doctor’s disease to a degree that it was not fatal but still granted him the extreme strength as well as less potent versions of the other symptoms. Frantically searching for something in the clinic, the man found what he was looking for, a biohazard suit. The man put the suit on and said “Bobby Clay, the man I was, is dead. Now I am what Dr. Plague made me. Patient Zero .” A hero was born. The police arrived and Dr.Plague regained consciousness. Dr.Plague swore that when he returned he would be less generous, he would make his plague stronger, deadlier, and that there would be no cure. He would watch the city die from sickness, and laugh. Omus postulated that if he were to escape perhaps he was to dangerous to live.